Vigilancia Tecnológica

Patches applied to teeth are known to have problems relating to the removal of the patch. A patch when used for attaching to teeth or a surrounding part of teeth. The patch includes a drug layer having a drug component and a backing layer which is positioned on one side of the drug layer and whose tensile strength is reduced by 50% or more by absorbing moisture. The patch is degradable and detachable by tooth brushing and wherein the tensile strength of the backing layer of the patch, which is measured in a state that moisture is sufficiently absorbed so that the moisture content rate does not change for 10 sec, and measured at an environment of temperature of 25°C using Zwick, DE/1494 universal testing machine at a rate of 0.1 mm/s, is reduced by 50% or more, compared to before moisture absorption and wherein the backing layer includes a water-insoluble polymer which is ethyl cellulose and at least one water-soluble polymer selected from the group consisting of polyalkyl vinyl ether-maleic acid copolymer (PVM/MA copolymer), polyvinyl alcohol, polyacrylic acid, Poloxamer 407, polyethyleneoxide (Polyox), polyvinyl pyrrolidone-vinyl acetate copolymer (PVP/VA copolymer), polyvinyl pyrrolidone (PVP), polyquaternium-11, polyquaternium-39, carboxypolymethylene (Carbomer), hydroxypropyl methyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, gelatin and sodium alginate, and wherein the backing layer comprises at least one plasticizer selected from the group consisting of castor oil and hydrogenated castor oil.