Vigilancia Tecnológica

A self-adhesive absorbable biological patch, comprising a base layer and an adhesive coating on the base layer. The base layer is a biological material, and the adhesive coating is a polyacrylic acid cross-linked copolymer grafted with a succinimide ester group, wherein the cross-linked copolymer optionally comprises a biodegradable polymer. The cross-linked copolymer is formed by polymerizing and cross-linking acrylic acid and/or acrylamide with an acrylated biodegradable polymer and acrylic acid-N-succinimide ester. The biological patch can be firmly bonded to the surface of a tissue, can be directly applied without additional preparation, is good in biocompatibility, has biodegradability, and can be used in common clinical scenarios such as tissue bonding, wound hemostasis, and low-pressure leakage of body fluids.